Description
Product Characteristics:
CCL26 is a recently discovered CC chemokine. It binds to the CCR3 receptor and is highly chemotactic for eosinophils and basophils.
Subcellular location: Secreted
Synonyms: C-C mot chemokine 26, CC chemokine IMAC, CCL 26, CCL26, CCL26_HUMAN, Chemokine C C mot ligand 26, Eotaxin-3, IMAC, Macrophage inflammatory protein 4-alpha, MIP 4a, MIP 4alpha, MIP-4-alpha, MIP4a, MIP4alpha, SCYA 26, SCYA26, Small inducible cytokine A26, Small inducible cytokine subfamily A Cys Cys member 26, Small inducible cytokine subfamily A member 26, Small-inducible cytokine A26, Thymic stroma chemokine 1, Thymic stroma chemokine-1, TSC 1, TSC-1, TSC1.
Target Information: This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008]